About this module
Review 04 Apr 2019
The aetiologies of iron deficiency are numerous and varied as are their associated investigation and treatment modalities. However, in the context of chronic kidney disease (CKD) iron deficiency requires specialist input. This module addresses iron deficiency in the context of CKD and alludes to the key aspects that under pin diagnostics and treatment. As with the optimal management of any medical condition a comprehensive understanding of the relevant physiology is required, in this case renal physiology and the physiology pertaining to absorption and transportation and storage of iron in its various forms. Functional vs absolute iron deficiency is explained, as are the pathophysiologies associated with both. Erythropoiesis-stimulating agents are discussed along with oral and intravenous therapeutic treatment options. Common obstacles encountered in the clinical setting are addressed such as when to consider intravenous iron replacement vs oral and the relevant safety aspects to consider therein. At the end of the module the reader should have a good understanding of how iron deficiency in patients with CKD differs from that of patients with iron deficiency from other causes. The reader should be able to incorporate this information into their clinical practice while also realising that this specialist area may require appropriate specialist consultation.
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